I was a Reservist in Savannah until I retired in 2016. At the time ME was established, most MEs in the area were assigned to Marine Safety Unit Savannah. A couple of years before I retired, all the MEs were pulled from the MSU and sent to various small boat stations. Most went to Station Tybee or Station Brunswick, and I think a couple went to Charleston or Mayport.
Many Reservists I worked with in Savannah were coming in from the Atlanta area, and others came from Florida, Alabama, and South Carolina. We had one who flew in from Oklahoma. Many Reservists have 4+ hour commutes.
I was lucky, I live in Savannah and spent all of my Reserve time drilling in Savannah. That was fortunate after 9/11, when everybody was called in on Title X and all of the Reservists from out of town were doubled up in hotel rooms and tripled up in apartments for two years. If I had not retired when I did, I would have been sent to Charleston, Jacksonville, or Wilmington, NC.
The biggest headache I saw the commuters to deal with was with the government arranged lodging. The process for requesting lodging seem to change a lot, and the constant reminder of "keep in mind, the USCG isn't really obligated to pay for your lodging" bit got stale.
I don't know what other people did, but when weather was bad, I would find ways for our out of town folks to arrange their Sunday schedule so that they could meet the hours required for two drills (each day was two drills) but still get on the road reasonably early on Sunday so that they could get as many miles behind them before it got too dark.
Most said the commute was worth it.
Good luck!